Automation Now and Then: Automation Fevers, Anxieties and Utopias

Fixture Design Automation and Optimization Techniques: Review and Future Trends

Fixture design is crucial part of manufacturing process. Fixture design is a critical design activity process, in which automation plays an integral role in linking computer-aided design (CAD) and computer-aided manufacturing (CAD). This paper presents a literature review in computer aided fixture design (CAFD) in terms of automation and optimization techniques over the past decades. First, the...

Schizophrenia: Then and Now

EPS—Then and Now

"Slime" played a brief and spectacular role in the 19th century founded by the theory of primordial slime by Ernst Haeckel. However, that substance was never found and eventually abandoned. Further scientific attention slowly began in the 1930s referring to slime as a microbial product and then was inspired by "How bacteria stick" by Costerton et al. in 1978, and the matrix material was conside...

Then and Now

Fluoroquinolones: then and now.

Fluoroquinolones were discovered in the 1960s as a derivative of the antimalarial drug chloroquine. Over the past 40 years, many fluoroquinolones have been developed for use in human and veterinary medicine. As with all classes of antibiotics, resistance to fluoroquinolones is a serious concern, and multiple avenues for resistance are being investigated. Resistance-associated point mutations in...